Men with Peyronie’s disease or penis curvature often seek medical attention in a number of ways, including painful erections, penile curvature or erectile dysfunction (ED). It is not surprisingly that Peyronie’s disease is often associated with erectile dysfunction (ED). Published reports indicate that between 30 to 80% of men may have erectile dysfunction (ED) associated with Peyronie’s disease and up to 50% may have erectile dysfunction (ED) before they develop Peyronie’s disease. Peyronie’s disease will affect men physically and psychologically. There is a misconception that the erectile dysfunction associated with PD is caused by the deformity and is not a frequent companion to Peyronie’s disease.

There is several factor may contribute to erectile dysfunction in men with Peyronie’s disease. Underlying conditions such as atherosclerosis or hardening of the arteries including diabetes, hypertension or high blood pressure may contribute in the development of erectile dysfunction in Peyronie’s disease sufferer. Psychologically distressed is also shown by men with Peyronie’s disease as there is changes to their penis. This psychological effect in turn will contribute to development of erectile dysfunction.

The studies about etiology or cause of the erectile dysfunction in patients with Peyronie’s disease have demonstrated repeatedly that the erectile dysfunction found in men with Peyronie’s disease is most commonly due to vascular insufficiency similar to the etiology found in the general public with erectile dysfunction alone. Peyronie’s disease can often cause poor erectile function. The penis may become firm up to the point of the plaque and remain soft beyond that point. In some instances, the patient may see a narrowed ‘b ottleneck’ or an ‘hourglass’ shape of the penis as well. The plaque can also prevent the penis from storing blood during erection. As a result of this, the patient may be unable to have intercourse because of a soft and curved penis.

The other factor why Peyronie’s disease has a link with erectile dysfunction is diabetes. Diabetes is one of the most common conditions associated with erectile dysfunction. A study show that in patients with diabetes mellitus, irrespective of type, the prevalence or occurrence of erectile dysfunction is approximately 50% (range 20 to 75%) with the prevalence dependent on patient age, duration of diabetes and severity of the diabetes. Other studies on multiple demographic have shown that up to 28% percent of men with Peyronie’s disease have diabetes mellitus.

Treatments for erectile dysfunction may encourage injury to the rigid penis in the susceptible individual thereby activating Peyronie’s disease, and erectile dysfunction, in the patient with Peyronie’s disease may occur most commonly due to underlying vascular disease. Therefore, the treatment of men with Peyronie’s disease and erectile dysfunction has been controversial. Several drugs is consider as the first line of the treatment, since men with Peyronie’s disease were not formally studied during clinical trials, the usage of this drugs is not recommended by some experts. One study suggest that patients with severe Peyronie’s disease and erectile dysfunction should be offered the choice of penile modeling over an inflatable penile implant to correct the curvature, as well as improve erectile function.

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